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Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque,
Nature Communications,
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A proteome-scale map of the SARS-CoV-2-human contactome,
Nature Biotechnology,
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A community challenge for a pancancer drug mechanism of action inference from perturbational profile data,
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Connecting chemistry and biology through molecular descriptors,
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Binary Interactome Models of Inner-Versus Outer-Complexome Organization,
bioRxiv,
2021,
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Identification and drug-induced reversion of molecular signatures of Alzheimers disease onset and progression in AppNL-GF, AppNL-F and 3xTg-AD mouse models,
Genome Medicine ,
2021, 13, Pubmed: 34702310,
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Haste makes waste: A critical review of docking-based virtual screening in drug repurposing for SARS-CoV-2 main protease (M-pro) inhibition,
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Identification of Broad-Spectrum MMP Inhibitors by Virtual Screening,
Molecules,
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Vaccines,
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Bioactivity descriptors for uncharacterized compounds,
Nature Communications,
2021, 12:1-13, Pubmed: 34168145,
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Anti-Inflammatory and Immunomodulatory Effects of the Grifola frondosa Natural Compound o-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κβ and MAPK,
Pharmaceutics,
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Natural variants suppress mutations in hundreds of essential genes,
Molecular systems biology,
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Environmental robustness of the global yeast genetic interaction network,
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Nucleic acids research,
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Systematic analysis of bypass suppression of essential genes,
Molecular Systems Biology,
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Personalized Cancer Therapy Prioritization Based on Driver Alteration Co-occurrence Patterns,
Genome Medicine,
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Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns,
Genome Medicine,
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Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs,
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Antigen-stimulated PBMC transcriptional protective signatures for malaria immunization,
Science Translational Medicine,
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Systematic genetics and single-cell imaging reveal widespread morphological pleiotropy and cell-to-cell variability,
Molecular Systems Biology,
2020, Pubmed: 32064787,
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A classifier to predict viral control after antiretroviral treatment interruption in chronic HIV-1 infected patients,
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In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases,
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Encircling the regions of the pharmacogenomic landscape that determine drug response,
Genome Medicine,
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Formatting biological big data for modern machine learning in drug discovery,
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Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline,
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Genome Medicine,
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Molecular & Cell Proteomics,
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An inter‐species protein–protein interaction network across vast evolutionary distance,
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Isolation of Human Colon Stem Cells Using Surface Expression of PTK7,
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Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage,
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The EHEC-host interactome reveals novel targets for the translocated intimin receptor,
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A Proteome-Scale Map of the Human Interactome Network,
Cell,
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An Second-generation Protein-Protein Interaction Network of Helicobacter pylori,
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The binary protein-protein interaction landscape of Escherichia coli,
Nature Biotechnology,
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Nucleic Acids Research,
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Towards a detailed atlas of protein-protein interactions,
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Structural Systems Pharmacology: the role of 3D structures in next generation drug development,
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Functional and Structural Analysis of C-Terminal BRCA1 Missense Variants,
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The proton-pump inhibitor lansoprazole enhances amyloid beta production,
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Interactome3D: adding structural details to protein networks,
Nature Methods,
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NetAligner – A network alignment server to compare complexes, pathways and whole interactomes,
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Mol Cell Proteomics,
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Genome Medicine,
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PSICQUIC and PSISCORE: accessing and scoring molecular interactions,
Nature Methods,
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Protein Sci,
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Interactome mapping suggests new mechanistic details underlying Alzheimer's disease,
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Revealing the molecular relationship between type 2 diabetes and the metabolic changes induced by a very-low-carbohydrate low-fat ketogenic diet,
Nutr Metab (Lond),
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Splitting statistical potentials into meaningful scoring functions: testing the prediction of near-native structures from decoy conformations,
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Dynamic interactions of proteins in complex networks: a more structured view,
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Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions,
BMC Systems Biology,
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Targeting and tinkering with interaction networks,
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2007
Shaping the future of interactome networks,
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