Researchers at the J. Craig Venter Institute and the Virginia Commonwealth University in the United States, in close collaboration with scientists at the Institute for Research in Biomedicine (Patrick Aloy, Roberto Mosca and Arnaud Ceol from IRB Barcelona), have published the first map of the molecular interaction of proteins—called the interactome—of Escherichia coli (E. coli).
This map allows researchers to start to understand the intricacies of the bacterial machinery. The study reveals around 25% (2,234) of the approx. 10,000 key interactions estimated for E. coli and covers about 70% of its proteome (the collection of proteins).
The study is published in Nature Biotechnology, one of the journals of reference for the scientific community, and its of high relevance due to the fundamental role that E. coli plays in white biotechnology, that is to say, for the production of large amounts of chemical material, such as artemisinin to treat malaria and insulin for diabetes.