Lídia Mateo

PhD Student

Structural Bioinformatics and Network Biology group
Institute for Research in Biomedicine (IRB)
Parc Científic de Barcelona
C/ Baldiri Reixac 10
08028 Barcelona - Spain

lidia.mateo <at> irbbarcelona.org

Research interests

I am interested in the use of biological networks as multi­plataform integration tools for the understanding of biological processes. In my PhD project, I would like to use network biology to move from the “one gene, one drug” reductionistic framework to the more comprehensive systems pharmacology point of view in order to understand inter­individual differences in treatment outcome. To achieve this goal, I will complement my background in evolutionary and functional genomics with the conceptual frameworks and methodologies that are currently used at Structural Bioinformatics and Network Biology group.

Previous working experience

I have investigated the role of SNPs and Transposable Elements in recent adaptive evolution in Drosophila melanogaster at Evolutionary and Functional Genomics Lab (http://biologiaevolutiva.org/gonzalez_lab) under the guidance of Josefa González. I have also participated in smaller collaborations with the Center for Research in Occupational Health (UPF), the Department of Animal Biology, Plant Biology and Ecology (UAB) and the Museum of Natural History of Barcelona.

Publications

Mateo L, Ullastres A, González J A transposable element insertion confers xenobiotic resistance in Drosophila. PLoS Genet. 2014 Aug 14;10(8):e1004560. doi: 10.1371/journal.pgen.1004560, [link]

Mateo L , González J Pogo­like transposases have been repeatedly domesticated into centromere- associated proteins. Genome Biol Evol. 2014 Jul 24;6(8):2008­16. doi: 10.1093/gbe/evu153, [link]